Useful links

Databases of drugs and drug targets

  • : medicinal chemistry and drug discovery databases
  • : detailed information on drugs and the protein sequences they interact with. Note that DrugBank is free for academic and non-profit use but commercial users require a license.
  • : a free database of chemical structures of small organic molecules and information on their biological activities
  • ZINC: A database containing commercially available compounds for structure-based virtual screening.

GPCR databases

  • : group of researchers in France on "G protein-coupled receptors - from physiology to drugs"
  • : Information system for G protein-coupled receptors (GPCRs)
  • : a database of G-proteins and their interaction with GPCRs
  • (Zhang Y, Devries ME, Skolnick J. PLoS Comput Biol. 2006 2(2):e13)

VGIC and LGIC databases

Nuclear Receptor databases

Enzyme databases

  • : A resource providing access to the data of the International Union of Biochemistry and Molecular Biology (IUBMB) Enzyme Nomenclature List, and which maintains the IUPAC standard formatting of chemical names.
  • : An expert curated database providing access to information and tools useful to the study of in-vivo post-translational modification of proteins of the kinome.

Transporter databases

  • : information on Solute Carrier transporter families

Antibody resources

  • , which hosts

Gene/protein databases

  • : A searchable, integrated, database that provides concise genomic related information, on all known and predicted human genes. Includes , the human disease database. Note that GeneCards is free for academic and non-profit use but commercial users require a license.
  • : integrates protein information from several allied databases into a single searchable resource providing protein family classification information, functional domain prediction and identification of other important sites on proteins.
  • : An automated system for constructing putative homology groups from the genomes of a wide range of eukaryotic species.
  • : Kyoto Encyclopedia of Genes and Genomes
  • : a human protein-centric knowledgebase providing access to a range of high-quality datasets with tools to mine them.
  • : a collection of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs)
  • : an ontological representation of protein-related entities by explicitly defining them and showing the relationships between them.
  • : a database of animal gene trees, encompassing inferred phylogenetic trees, predicted orthologues/parologues and the evolutionary history of genes.
  • : a database of the transcriptome providing information on protein similarities, gene expression, cDNA clones, and genomic location.
  • : resource for protein sequence and functional information

Metabolite databases

Other relevant resources

  • : a Web server for mining of 7TM proteins

Journals

Other useful links

http://pillsbank.net